### Feasibility of Wave Health to Monitor Electronic Patient-Reported Outcomes (ePROs) in Prostate Cancer Patients

### Highlights

- Wave Health app achieved **93.3%** **ePRO compliance** in collecting ePROs for inpatients with prostate cancer.
- Most patients (**80%**) **completed ePROs** without needing assistance.
- Most **health care providers** (**97.6%**) and **patients** (**95.4%**) found the platform **useful**.
- **High compliance rates** were observed regardless of age, education, or tech confidence.

### Background

Benefits of electronic patient-reported outcomes (ePROs) are well established, but concerns exist around their applicability in certain cancer patient populations. This multicenter study aimed to evaluate the feasibility and compliance of a novel platform, Wave Health, to automate the collection of ePROs among patients undergoing systemic treatment for prostate cancer.

### Patients and Methods

The study was conducted across eight Spanish hospitals where prostate cancer patients able to use smartphones were asked to download the Wave Health app and fill out different ePRO questionnaires weekly for 12 weeks. The primary outcome was compliance with questionnaire completion.

#### Spain Study Background 	 – Full study article is available here: [Feasibility of Wave Health to Monitor Electronic Patient-Reported Outcomes (ePROs) in Prostate Cancer Patients](https://www.esmorwd.org/article/S2949-8201(25)00066-9/fulltext)

### Results

Eighty-seven patients were enrolled (48% aged >70 years; 48% >high school educated). The compliance rate using the app was 93.3% to complete 19 scheduled ePRO questionnaires during their participation, and the acceptance rate was 94.3%. Most patients described the app as intuitive and completed most ePROs (>80%) ‘without help’, even though 28.7% reported a lack of technology confidence. The mean Cancer Health Literacy Test-30-Spanish (CHLT-30-DKspa) score increased from 22.3 at baseline to 23.2 at week 12. Fatigue, weakness, and poor sleep were the most common symptoms reported by patients. Most health care providers (97.6%) rated the platform as ‘very useful’, ‘useful’, or ‘somewhat useful.’

### Conclusion

This study demonstrated that ePRO collection via the Wave Health platform is feasible, with high rates of compliance, acceptance, and satisfaction among prostate cancer patients under systemic treatment regardless of age, education, or level of tech confidence, and that the app is perceived as useful among health care providers.

#### Download the full ESMO [article here](https://www.wavehealth.app/s/ESMO-JOURNAL-PROWAVE-STUDY.pdf).

#### About ESMO

[_ESMO Real-World Data and Digital Oncology_](https://www.esmo.org/about-esmo/discover-esmo-journals/esmo-real-world-data-and-digital-oncology) is a peer-reviewed, open-access journal by the European Society for Medical Oncology (ESMO).

#### About Wave Health

Born from a personal cancer experience, Wave Health is a trusted, comprehensive digital health platform designed to transform the management and understanding of chronic conditions in large patient populations. Comprised of a patient app and care portal, the platform efficiently collects, manages, and analyses patient-reported data from outside the clinical setting. The platform generates actionable insights to drive patient engagement and adherence, and to help medical teams manage individual treatments. For more information, please visit [www.wavehealth.app](https://www.wavehealth.app/).

#### Source

Gomez Mediavilla, B, et al. “Feasibility of Wave Health to Monitor Electronic Patient-Reported Outcomes (ePROs) in Prostate Cancer Patients”. ESMO Real World Data and Digital Oncology, Vol 10, Dec. 2025.

*Barcelona, Spain and El Segundo, California* – *Nov 18*

**ACCEPTED ABSTRACTS INCLUDE:**

**Spain PRO-WAVE1 study** and **UK feasibility study.**

* * *

**Treatment Technologies & Insights, Inc. (TTI)** parent company of the Wave Health digital health platform, today announced that ISPOR has accepted two study abstracts assessing the Wave Health tool designed to help both patients and care teams. A globally recognized digital health solution, Wave Health engages patients and streamlines care workflows through automated communication and remote monitoring.

The results showcased NHS stakeholders positively reviewing Wave Health to impact cancer management. Notably, the platform had the potential to support clinical decision making and reduce administrative workflow.

TTI CEO Matt Lashey said: “We are honored to have multiple studies recognized at ISPOR.”

#### About Health Innovation Oxford and Thames Valley

Health Innovation Oxford and Thames Valley works with the NHS, research, and industry to identify, develop, and spread innovation that will benefit patients. Email: info@healthinnovationoxford.org / Web: [www.healthinnovationoxford.org](https://www.healthinnovationoxford.org/)

#### About ISPOR Conference

The ISPOR Europe 2024 conference will be held 17–20 November 2024 in Barcelona, Spain. The conference program centers on understanding and improving the health and well-being of people across the globe.